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  • ly substituted with one or more substituents as described in the definition of aryl given above, alipid, including a phospholipid, an amino acid, peptide, or cholesterol; andR.sup.3 is acyl, alkyl, phosphate, or other pharmaceutically acceptable leaving group which when administered in vivo, is capable of being cleaved to the parent compound.In a second embodiment, a 2'-fluoronucleoside is provide
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