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  • J Clin Oncol. 1998;16(8):2817-2824.Pioneered the use of chemotherapy given before surgery to shrink tumors of the breast, pancreas, lung and other organs, allowing them to be surgically removed with less damage to surrounding normal tissues.Hortobagyi GN, Spanos W, Montague ED, Buzdar AU, Yap HY, Blumenschein GR. Treatment of locoregionally advanced breast cancer with surgery, radiotherapy and com
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