Flavonoids in grape seeds have also been reported to exhibit activities against peptic ulcer (Saito et al. 1998) and several dermal disorders (Bomser et al. 1999).Antioxidant activityPhenolics including flavonoids and related polyphenols from wine and grape seeds have generated remarkable interest based on several reports (both in vivo and in vitro) of their antioxidant and free radical scavenging