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  • As demonstrated by the following examples, it has now been shown that tethered TGF-?? can also be used to induce formation of ECM by cells, including cells such as smooth muscle cells and chondrocytes. [0031] Tethers [0032] For the matrix-enhancing molecules to induce formation of ECM, it is necessary for the molecule to be tethered to the scaffold by a tether.
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