ue or A is a hydrogen atom and B and D together are a methylene bridge, where R1 besides the aforementioned residues may be a possibly substituted hydrocarbon residue with up to 10 C atoms, a possibly substituted amino group, a hydroxy or C1-8 alkoxy, mercapto or thioalkyl group, R2 is a methyl or ethyl residue, and R3 /R4 represents the usual combination of substituents on the C17 atom in steroid