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| - Agent: Heslin Rothenberg Farley & Mesiti PC20100317691 - Isoquinolone compounds as subtype-selective agonists for melatonin receptors mt1 and mt2: R1, R2, R3, R4 and R7 are independently H, halo, alkyloxyl, alkyl or hydroxyl, provided that one of R1, R2, R3 and R7 is X???(CH2)n???R8; R5 is alkyl or arylalkyl; R6 is H or alkyl; X is a bond, O, S, SO, SO2, CO or NH; n=0-10; R8 is alkenyl,...
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