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| - Genetic factors are also involved, as is smoking, caffeine consumption, the chronic use of certain drugs (corticosteroids and antiinflammatories), nutritional deficiencies (vitamin D and calcium), biotype (female, fair-skinned, slim), a sedentary lifestyle and diseases such as malabsorption syndromes, diabetes mellitus and hypoparathyroidism. 2,6 Most of the collagen in the human body is located i
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