Most Effective but Underutilized Treatments : LDN, EFT and Sauna are the most effective treatments that are underutilized..It does not show it but methylation is one of the more effective but underutilized treatments as well - go to the link below and hover over the dots to see what they all refer to. http://curetogether.com/chronic-fatigue-syndrome/ig/treatment-effectiveness-vs-popularity