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  • The reaction may be conveniently carried out in a solvent such as toluene at an elevated temperature, e.g. the reflux temperature, using a catalyst such as tris(dibenzylideneacetone)-dipalladium(0), a phosphine ligand such as 2,2???-bis(diphenylphosphino)-1,1???-binaphthyl, and a base such as caesium carbonate.
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