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  • ast about 4-fold, at least about 5-fold, or more compared to baseline or compared to placebo control. [0059] In some of these embodiments, an ???effective amount??? of a TLR agonist is an amount that increases the single breath DLco by at least about 15%, at least about 20%, at least about 30%, at least about 40%, at least about 50%, at least about 60%, at least about 70%, at least about 80%, at l
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