Factor, Platelet Derived Endothelial Cell Growth Factor, Hepatocyte Growth Factor, DEL-1, Angiostatin-1 and Pleiotrophin. [0066] For treatment of cancers and tumors, angiostatic agents may be used including antibodies or other antagonists to angiogenic agents as defined above, such as antibodies to VEGF or Angiotensin 2 and cytotherapeutic agents such as cytotoxic agents, chemotherapeutic agents,