Van Puyvelde Katrien K Frailty in Ageing (FRIA) Research Group and Gerontology Department, Vrije Universiteit Brussel, Brussels, Belgium; Department of Geriatric Medicine, Universitair Ziekenhuis Brussel, Brussels, - - 2014 Aging is associated with a chronic low-grade inflammatory status that contributes to chronic diseases such as age-related muscle wasting, kidney disease, and diabetes mellitus.