Major risk factors include:Family history of cardiomyopathy, heart failure or sudden cardiac arrest (SCA)A disease or condition that can lead to cardiomyopathy, such as coronary heart disease, heart attack, or a viral infection that inflames the heart muscleDiabetes or other metabolic diseases, or severe obesityDiseases that can damage the heart, such as hemochromatosis, sarcoidosis or amyloidosis