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| - Magnesium deficiency is one of the many causes of RLS. RLS can be caused by deficiencies of magnesium, B vitamins especially folate and vitamin B12, iron, potassium and vitamin E. RLS can be genetic, from neurologic lesions, pregnancy (folate deficiency or high level of estrogen), diabetes, sleep apnea, uremia, thyroid disease, peripheral neuropathy, Parkinson's disease and certain auto-immune dis
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