decades I have to say that I am not aware of beta-blockers been harmful in Negroes (I started my career in South Africa and most of my patients were Negroes).Interestingly enough though ACE inhibitors (used to treat high blood pressure and some forms of heart failure) appear not to work at all well in Negroes.There are lots of other examples of this sort in different racial groups.BTW - no axe to