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  • Advantageously, compounds of the following formula are disclosed in the present invention. ##STR116## and the pharmaceutically acceptable salts thereof, wherein: A is: ##STR117## except when R2 equals H, Y equals O, Z equals N and there is a 5?? H, R6 and R3 cannot be independently selected from H, C1-8 alkyl, C3-6 cycloalkyl, phenyl or when R6 and R3 are taken together with the adjacent N to form
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