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  • A more practical, and the preferred embodiment of the invention, is a composition comprising an opioid agonist analgesic medication and nalmefene, in amounts of each drug, such that when the composition is administered to yield a prescribed amount of administered opioid agonist analgesic, an amount of nalmefene is administered such that, i) at therapeutic doses of opioid agonist analgesic, an amou
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