4and f=1-3, ???CH2)g???SO2???(CH2)h??? where g=1-2 and h=1-2, where i=1 or 2, or where j is 1 or 2 and Z is an amino group, alkylamino group, or piperidyl amino group; and B is a substituted or unsubstituted C1 to C6 alkyl group; W is a hydrogen or C(O)R where R is as defined above; and pharmaceutically acceptable salts, esters or hydrates thereof. 2.