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  • Recent studies suggest that ascorbate may be the primary extracellular antioxidant in plasma (Frei B. et al. (1989) PNAS (USA) 86:6377-6381) and that other physiologic reducing compounds such as vitamin E, are maintained in the reduced state at the expense of ascorbate (Maguire J. J. et al. (1989) J. Biol.
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