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  • Adjustment for socioeconomic group, smoking, and other factors, including medical history, substantially reduced the RR estimates that were adjusted by age and region only (from 1.52 to 1.22 for menopause before 45 y, and from 1.23 to 1.08 for menopause at age 45???49 y, compared to 50 y and over, Table 3).
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